小鼠抗S100A4单克隆抗体

Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

WB, IP

Name of antibody:

S100A4

Immunogen:

Fusion protein of human S100A4

Full name:

S100 calcium binding protein A4

Synonyms:

42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98

SwissProt:

P26447

WB Predicted band size:

12 kDa

WB Positive control:

Hela and A549 cell lysates

WB Recommended dilution:

500-2000