兔抗NF1多克隆抗体

Background:

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

NF1

Immunogen:

Synthetic peptide of human NF1

Full name:

neurofibromin 1

Synonyms:

WSS; NFNS; VRNF

SwissProt:

P21359

ELISA Recommended dilution:

500-1000

IHC positive control:

Human liver cancer and human gastric cancer

IHC Recommend dilution:

40-250