兔抗APOE多克隆抗体

Background:

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants

Applications:

WB

Name of antibody:

APOE

Immunogen:

Synthesized peptide derived from C-terminal of human APOE.

Full name:

apolipoprotein E

Synonyms：

AD2; LPG; LDLCQ5

SwissProt:

P02649

WB Predicted band size:

36 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000