兔抗EHD3多克隆抗体

Background:

ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis . In vitro causes tubulation of endocytic membranes . Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 dopamine receptor . Plays a role in cardiac protein trafficking probably implicating ANK2. Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction .

Applications:

ELISA, WB

Name of antibody:

EHD3

Immunogen:

Synthetic peptide of human EHD3

Full name:

EH domain containing 3

Synonyms:

PAST3

SwissProt:

Q9NZN3

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

61 kDa

WB Positive control:

NIH/3T3 cell and Human heart tissue lysates

WB Recommended dilution:

200-1000