兔抗ABCE1多克隆抗体

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

ABCE1

Immunogen:

Fusion protein of human ABCE1

Full name:

ATP-binding cassette, sub-family E (OABP), member 1

Synonyms：

RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI

SwissProt:

P61221

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

67 kDa

WB Positive control:

NIH/3T3 and SKOV3 cells, human ovarian cancer tissue

WB Recommended dilution:

500-2000