| Background: | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | TNF | 
| Immunogen: | Synthetic peptide of human TNF | 
| Full name: | tumor necrosis factor | 
| Synonyms: | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha | 
| SwissProt: | P01375 | 
| ELISA Recommended dilution: | 5000-10000 | 
| IHC positive control: | Human colorectal cancerHuman liver cancer | 
| IHC Recommend dilution: | 20-100 | 
	
	
 
 
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