| Background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | TNFRSF8 | 
| Immunogen: | Synthetic peptide of human TNFRSF8 | 
| Full name: | tumor necrosis factor receptor superfamily, member 8 | 
| Synonyms: | CD30; Ki-1; D1S166E | 
| SwissProt: | P28908 | 
| ELISA Recommended dilution: | 1000-5000 | 
| IHC positive control: | Human Lymphoma and Human thyroid cancer | 
| IHC Recommend dilution: | 50-200 | 
	
	 
 
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