兔抗GRK3多克隆抗体

IHC Recommend dilution:

50-200

IHC positive control:

Human thyroid cancer and Human colon cancer

SwissProt:

P35626

Synonyms:

BARK2; ADRBK2

Full name:

G protein-coupled receptor kinase 3

Immunogen:

Fusion protein of human GRK3

Name of antibody:

GRK3

Applications:

ELISA, IHC

Background:

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]