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IHC Recommend dilution: |
50-200 |
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IHC positive control: |
Human thyroid cancer and Human colon cancer |
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SwissProt: |
P35626 |
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Synonyms: |
BARK2; ADRBK2 |
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Full name: |
G protein-coupled receptor kinase 3 |
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Immunogen: |
Fusion protein of human GRK3 |
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Name of antibody: |
GRK3 |
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Applications: |
ELISA, IHC |
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Background: |
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008] |
