兔抗KCNQ3多克隆抗体

Background:

This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

KCNQ3

Immunogen:

Synthetic peptide of human KCNQ3

Full name:

potassium channel, voltage gated KQT-like subfamily Q, member 3

Synonyms:

EBN2; BFNC2; KV7.3

SwissProt:

O43525

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100