兔抗GRIA3多克隆抗体

Background:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Applications:

ELISA, IHC

Name of antibody:

GRIA3

Immunogen:

Synthetic peptide of human GRIA3

Full name:

glutamate ionotropic receptor AMPA type subunit 3

Synonyms:

GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3

SwissProt:

P42263

ELISA Recommended dilution:

500-1000

IHC positive control:

Human thyroid cancer and Human ovarian cancer

IHC Recommend dilution:

50-100