兔抗DEFA5多克隆抗体

Background:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Applications:

ELISA, IHC

Name of antibody:

DEFA5

Immunogen:

Synthetic peptide of human DEFA5

Full name:

defensin, alpha 5, Paneth cell-specific

Synonyms:

DEF5; HD-5

SwissProt:

Q01523

IHC positive control:

Human gastric cancer and human brain

IHC Recommend dilution:

15-50