兔抗FRS2(Ab-196) 多克隆抗体

Background:

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Applications:

WB

Name of antibody:

FRS2(Ab-196)

Immunogen:

Synthesized non-phosphopeptide derived from human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N).

Full name:

fibroblast growth factor receptor substrate 2

Synonyms：

SNT; SNT1; FRS2A; SNT-1; FRS2alpha

SwissProt:

Q8WU20

WB Predicted band size:

57 kDa

WB Positive control:

HepG2 cells lysate

WB Recommended dilution:

500-3000