兔抗YBX1(Phospho-Ser102) 多克隆抗体

Background:

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.

Applications:

WB

Name of antibody:

YBX1(Phospho-Ser102)

Immunogen:

Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.

Full name:

Y box binding protein 1

Synonyms：

YB1; BP-8; CSDB; DBPB; YB-1; CSDA2; NSEP1; NSEP-1; MDR-NF1

SwissProt:

P67809

WB Predicted band size:

36 kDa

WB Positive control:

HepG2 cells lysates treated with PMA

WB Recommended dilution:

500-1000