兔抗ALDOA多克隆抗体

Background:

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Applications:

ELISA, WB, IHC

Name of antibody:

ALDOA

Immunogen:

Fusion protein of human ALDOA

Full name:

Aldolase A, fructose-bisphosphate

Synonyms:

ALDA; GSD12

SwissProt:

P04075

IHC positive control:

Human gastric cancer and human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

39 kDa

WB Positive control:

A549 and hela cells

WB Recommended dilution:

200-1000