兔抗EGFR (Phospho-Tyr1197)多克隆抗体

Background:

Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

Applications:

WB, IHC

Name of antibody:

EGFR (Phospho-Tyr1197)

Immunogen:

Synthetic peptide of human EGFR (Phospho-Tyr1197)

Full name:

epidermal growth factor receptor (Phospho-Tyr1197)

Synonyms：

ERBB; HER1; mENA; ERBB1; PIG61

SwissProt:

P00533

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

175 kDa

WB Positive control:

HUVEC cells untreated or treated with EGF

WB Recommended dilution:

500-1000