兔抗SIRT5多克隆抗体

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

SIRT5

Immunogen:

Synthetic peptide of human SIRT5

Full name:

Sirtuin 5

Synonyms:

SIR2L5

SwissProt:

Q9NXA8

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

34 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000