兔抗ALDH1A1/ALDH1A2/ALDH1A3多克隆抗体

Background:

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

ALDH1A1/ALDH1A2/ALDH1A3

Immunogen:

Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3

Full name:

Aldehyde dehydrogenase 1 family, member A1/2/3

Synonyms：

ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1; RALDH2, RALDH2-T, RALDH(II); ALDH6, RALDH3, ALDH1A6

SwissProt:

P00352/O94788/P47895

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

20-50

WB Predicted band size:

57 kDa

WB Positive control:

Human liver cancer tissue

WB Recommended dilution:

500-1000