兔抗SELL多克隆抗体

Background:

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

SELL

Immunogen:

Synthetic peptide of human SELL

Full name:

selectin L

Synonyms:

TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1

SwissProt:

P14151

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

20-100