兔抗RNF19A多克隆抗体

Background:

This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

RNF19A

Immunogen:

Synthetic peptide corresponding to a region derived from 102-117 amino acids of human RNF19A

Full name:

ring finger protein 19A, RBR E3 ubiquitin protein ligase

Synonyms:

RNF19

SwissProt:

Q9NV58

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human liver cancer;

IHC Recommended dilution:

10-50