兔抗FAT1多克隆抗体

Background:

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Applications:

ELISA, IHC

Name of antibody:

FAT1

Immunogen:

Synthetic peptide of human FAT1

Full name:

FAT atypical cadherin 1

Synonyms：

FAT; ME5; CDHF7; CDHR8; hFat1

SwissProt:

Q14517

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100