兔抗EVI2B多克隆抗体

Background:

EVI2B, also known as CD361. CD361 is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.

Applications:

ELISA, IHC

Name of antibody:

EVI2B

Immunogen:

Synthetic peptide of human EVI2B

Full name:

ecotropic viral integration site 2B

Synonyms:

EVDB; CD361; D17S376

SwissProt:

P34910

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

20-100