兔抗MRPS24多克隆抗体

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene.

Applications:

ELISA, IHC

Name of antibody:

MRPS24

Immunogen:

Fusion protein of human MRPS24

Full name:

mitochondrial ribosomal protein S24

Synonyms:

S24mt; bMRP47; HSPC335; MRP-S24; bMRP-47

SwissProt:

Q96EL2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human cervical cancer

IHC Recommend dilution:

50-300