兔抗FZD8多克隆抗体

Background:

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Applications:

ELISA, IHC

Name of antibody:

FZD8

Immunogen:

Synthetic peptide of human FZD8

Full name:

frizzled family receptor 8

Synonyms：

FZ-8; hFZ8

SwissProt:

Q9H461

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human esophagus cancer and Human liver cancer

IHC Recommend dilution:

50-200