兔抗PSMB2多克隆抗体

Background:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

PSMB2

Immunogen:

Fusion protein of human PSMB2

Full name:

proteasome subunit beta 2

Synonyms:

HC7-I

SwissProt:

P49721

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and Human breast cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

23 kDa

WB Positive control:

293T, Jurkat, HT29, K562, LOVO, Hela and HepG2 cell lysates

WB Recommended dilution:

1000-5000