小鼠抗SERPINB1单克隆抗体

Background:

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Applications:

WB, IHC, FC

Name of antibody:

SERPINB1

Immunogen:

Fusion protein of human SERPINB1

Full name:

serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1), transcript variant 1

Synonyms:

EI; ELANH2; HEL57; LEI; M/NEI; MNEI; PI-2; PI2

SwissProt:

P30740

IHC positive control:

adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue; human kidney tissue and human pancreas tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

43 kDa

WB Positive control:

HepG2, Hela, A549, COS7, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000