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021-54845833/15800441009
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Background: |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GRIK1 |
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Immunogen: |
Synthetic peptide of human GRIK1 |
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Full name: |
glutamate ionotropic receptor kainate type subunit 1 |
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Synonyms: |
EAA3; EEA3; GLR5; GLUR5; GluK1; gluR-5 |
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SwissProt: |
P39086 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
20-100 |
