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中文名称：兔抗APBA2多克隆抗体
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Background: |
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
APBA2 |
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Immunogen: |
Synthetic peptide of human APBA2 |
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Full name: |
amyloid beta (A4) precursor protein-binding, family A, member 2 |
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Synonyms： |
X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091 |
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SwissProt: |
Q99767 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
100-300 |
