兔抗GUCY1B2多克隆抗体

Background:

Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

Applications:

ELISA, IHC

Name of antibody:

GUCY1B2

Immunogen:

Synthetic peptide of human GUCY1B2

Full name:

guanylate cyclase 1 soluble subunit beta 2 (pseudogene)

Synonyms:

GC-SB2

SwissProt:

O75343

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human tonsil

IHC Recommend dilution:

20-100