小鼠抗CAPN2单克隆抗体

Background:

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

Applications:

WB, FC

Name of antibody:

CAPN2

Immunogen:

Fusion protein of human CAPN2

Full name:

calpain 2, (m/II) large subunit (CAPN2), transcript variant 1

Synonyms:

CANP2; CANPL2; CANPml; mCANP

SwissProt:

P17655

WB Predicted band size:

80 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, PC12 cell lysates

WB Recommended dilution:

1000-5000