兔抗ANGPT1多克隆抗体

Background:

This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

ANGPT1

Immunogen:

Full length fusion protein

Full name:

angiopoietin 1

Synonyms：

AGP1; AGPT; ANG1

SwissProt:

Q15389

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human colon cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

58 kDa

WB Positive control:

Human prostate tissue and testis tissue lysates

WB Recommended dilution:

500-2000