兔抗ICAM1多克隆抗体

Background:

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Applications:

ELISA, WB, IHC

Name of antibody:

ICAM1

Immunogen:

Synthetic peptide of human ICAM1

Full name:

intercellular adhesion molecule 1

Synonyms：

BB2; CD54; P3.58

SwissProt:

P05362

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and Human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

58 kDa

WB Positive control:

Huvec, hela and raji cells

WB Recommended dilution:

500-2000