兔抗FARP2多克隆抗体

Background:

Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).

Applications:

ELISA, IHC

Name of antibody:

FARP2

Immunogen:

Fusion protein of human FARP2

Full name:

FERM, ARH/RhoGEF and pleckstrin domain protein 2

Synonyms:

FIR; FRG; PLEKHC3

SwissProt:

O94887

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

50-200