兔抗GJA1多克隆抗体

Background:

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

Applications:

ELISA, IHC

Name of antibody:

GJA1

Immunogen:

Fusion protein of human GJA1

Full name:

gap junction protein alpha 1

Synonyms:

HSS; CMDR; CX43; EKVP; GJAL; ODDD; AVSD3; HLHS1; PPKCA

SwissProt:

P17302

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human brain

IHC Recommend dilution:

30-150