兔抗HDAC2多克隆抗体

IHC Recommend dilution:

25-100

IHC positive control:

Human ovarian cancer and Human colon cancer

ELISA Recommended dilution:

1000-5000

SwissProt:

Q92769

Synonyms：

HD2, RPD3, YAF1

Full name:

histone deacetylase 2

Immunogen:

Synthetic peptide of human HDAC2

Name of antibody:

HDAC2

Applications:

ELISA, IHC

Background:

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.