小鼠抗FTO单克隆抗体

Background:

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Applications:

WB, IHC

Name of antibody:

FTO

Immunogen:

Fusion protein of human FTO

Full name:

FTO, alpha-ketoglutarate dependent dioxygenase

Synonyms:

GDFD; ALKBH9; BMIQ14

SwissProt:

Q9C0B1

IHC positive control:

Human breast tissue and Human ovarian cancer; Human pancreas tissue and Human endometrium tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

58 KD

WB Positive control:

Jurkat, Hela, HepG2, 293T, SH-SY5Y cell lysates

WB Recommended dilution:

500-2000