兔抗COPS8多克隆抗体

Background:

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications:

ELISA, WB, IHC

Name of antibody:

COPS8

Immunogen:

Fusion protein of human COPS8

Full name:

COP9 signalosome subunit 8

Synonyms:

COP9; CSN8; SGN8

SwissProt:

Q99627

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer; Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

23 kDa

WB Positive control:

Human kidney tissue and Human fetal liver tissue, Hela cell lysates

WB Recommended dilution:

200-1000