兔抗LZTS1多克隆抗体

Background:

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Applications:

ELISA, IHC

Name of antibody:

LZTS1

Immunogen:

Synthetic peptide of human LZTS1

Full name:

leucine zipper, putative tumor suppressor 1

Synonyms：

F37; FEZ1

SwissProt:

Q9Y250

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

25-100