兔抗CHAT多克隆抗体

Background:

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Applications:

ELISA, IHC

Name of antibody:

CHAT

Immunogen:

Fusion protein of human CHAT

Full name:

choline O-acetyltransferase

Synonyms:

CMS6; CMS1A; CMS1A2; CHOACTASE

SwissProt:

P28329

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100