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抗 原： JAK3(Ab-785)
技术规格
Background:
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Applications:
WB, IHC
Name of antibody:
JAK3(Ab-785)
Immunogen:
Synthesized non-phosphopeptide derived from human JAK3 around the phosphorylation site of tyrosine 785 (S-D-Y(p)-E-L).
Full name:
Janus kinase 3
Synonyms：
JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN
SwissProt:
P52333
IHC positive control:
Human brain tissue
IHC Recommend dilution:
50-100
WB Predicted band size:
125 kDa
WB Positive control:
Jurkat cells lysate
WB Recommended dilution:
500-3000
