兔抗JAK3(Ab-785) 多克隆抗体

Background:

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Applications:

WB, IHC

Name of antibody:

JAK3(Ab-785)

Immunogen:

Synthesized non-phosphopeptide derived from human JAK3 around the phosphorylation site of tyrosine 785 (S-D-Y(p)-E-L).

Full name:

Janus kinase 3

Synonyms：

JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN

SwissProt:

P52333

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

125 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000