兔抗ETV2多克隆抗体

Background:

ETS translocation variant 2 (ETV2), also known as ETSRP and ER71, is a 37 kDa transcription factor that is expressed in presumptive vascular progenitor cells. It plays an important role in vascular development by promoting the expansion of hemangioblasts and vascular endothelial cells while inhibiting differentiation into cardiomyocytes. It contains one ETS DNA binding domain (aa 234-314). Within aa 125-231, mouse ETV2 shares 54% and 85% aa sequence identity with human and rat ETV2, respectively.

Applications:

ELISA, IHC

Name of antibody:

ETV2

Immunogen:

Synthetic peptide of human ETV2

Full name:

ETS variant 2

Synonyms:

ER71; ETSRP71

SwissProt:

O00321

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

10-50