兔抗BTK多克隆抗体

Background:

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

BTK

Immunogen:

Fusion protein of human BTK

Full name:

Bruton tyrosine kinase

Synonyms:

AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1

SwissProt:

Q06187

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human brain

IHC Recommend dilution:

25-100