小鼠抗PCMT1单克隆抗体

Background:

This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

WB

Name of antibody:

PCMT1

Immunogen:

Fusion protein of human PCMT1

Full name:

protein-L-isoaspartate (D-aspartate) O-methyltransferase

Synonyms:

PIMT

SwissProt:

P22061

WB Predicted band size:

25 KD

WB Positive control:

Hela, Jurkat, MCF7, K562 cell lysates

WB Recommended dilution:

500-2000