小鼠抗SWAP70单克隆抗体

Background:

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

Applications:

WB, IP

Name of antibody:

SWAP70

Immunogen:

Fusion protein of human SWAP70

Full name:

SWAP switching B-cell complex subunit 70

Synonyms:

HSPC321; SWAP-70

SwissProt:

Q9UH65

WB Predicted band size:

69 kDa

WB Positive control:

COS7, 293T, C6, 3T3 and Hela cell lysates

WB Recommended dilution:

1000-5000