兔抗KANK2多克隆抗体

Background:

Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.

Applications:

IHC, IF

Name of antibody:

KANK2

Immunogen:

Synthesized peptide derived from internal of human KANK2.

Full name:

KN motif and ankyrin repeat domains 2

Synonyms：

SIP; MXRA3; ANKRD25

SwissProt:

Q63ZY3

IHC positive control:

Human heart tissue

IHC Recommend dilution:

50-100

IF positive control:

A549 cells

IF Recommend dilution:

100-500