小鼠抗CFL1单克隆抗体

Background:

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Applications:

ELISA, WB

Name of antibody:

CFL1

Immunogen:

Fusion protein of human CFL1

Full name:

cofilin 1

Synonyms:

CFL; cofilin; HEL-S-15

SwissProt:

P23528

WB Predicted band size:

19 kDa

WB Positive control:

BGC823 whole cell lysate

WB Recommended dilution:

1000-5000