兔抗LPIN1多克隆抗体

Background:

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Applications:

ELISA, IHC

Name of antibody:

LPIN1

Immunogen:

Synthetic peptide of human LPIN1

Full name:

lipin 1

Synonyms:

PAP1

SwissProt:

Q14693

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer;

IHC Recommend dilution:

20-100