小鼠抗IRF3单克隆抗体

Background:

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

WB

Name of antibody:

IRF3

Immunogen:

Fusion protein of human IRF3

Full name:

interferon regulatory factor 3

Synonyms:

IIAE7

SwissProt:

Q14653

WB Predicted band size:

47 KD

WB Positive control:

Hela, Jurkat, K562, 293T, MCF7, Mouse heart tissue, Mouse spleen tissue lysates

WB Recommended dilution:

200-1000