小鼠抗RCAN1单克隆抗体

Background:

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Applications:

WB

Name of antibody:

RCAN1

Immunogen:

Fusion protein of human RCAN1

Full name:

regulator of calcineurin 1

Synonyms:

CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78

SwissProt:

P53805

WB Predicted band size:

28 KD

WB Positive control:

Jurkat cell, Mouse brain tissue lysates

WB Recommended dilution:

500-2000