| Background: | Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | FOXN1 | 
| Immunogen: | Synthetic peptide of human FOXN1 | 
| Full name: | forkhead box N1 | 
| Synonyms: | WHN, RONU, FKHL20 | 
| SwissProt: | O15353 | 
| ELISA Recommended dilution: | 1000-5000 | 
| IHC positive control: | Human cervical cancer | 
| IHC Recommend dilution: | 25-100 | 

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 021-54845833/15800441009
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