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中文名称：APP抗原（重组蛋白）
英文名称：APP Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
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Fusion protein corresponding to N terminal 304 amino acids of human APP |
技术规格
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Full name: |
amyloid beta (A4) precursor protein |
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Synonyms: |
AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma |
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Swissprot: |
P05067 |
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Gene Accession: |
BC004369 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. |
